Portrait of Claudia Rangel

Hired in 2006, Claudia Rangel-Escareño is an adjunct professor of mathematics at Claremont Graduate University’s Institute of Mathematical Sciences and director of the Computational Genomics Department at Mexico’s National Institute of Genomic Medicine.

Rangel-Escareño’s research interests are in computer-intensive methods in statistics and probability for applications in genomics and molecular biology, as well as microarray data analysis and bioinformatics. She also researches probabilistic modeling, with particular interest in State-Space modeling of time series microarray data to infer gene regulatory networks. In addition, she performs integrative and functional genomics in cancer research.

The National Institute of Genomic Medicine is a national and international leader in genomic research. Its main objective is to contribute to the care of the health of Mexicans through the development of scientific research projects with advanced technology and the generation of innovative ways to improve health care through genomic applications. Her recent research there has focused on the expression of microRNAs in the serum of postmenopausal women, searching for a noninvasive biomarker of bone metabolism for diagnosing osteoporosis.

Rangel-Escareño is a Fellow of the National Council of Science and Technology and has been invited as a speaker among others, by the Federal Institute of Technology in Zurich, Switzerland, and the Ludwig-Maximilians University in Munich, Germany. She has 23 publications and has published three book chapters. She is a member of the prestigious National Research System (SNI), Level I.

Co-authored with Edith A. Fernández-Figueroa, Valeria Espinosa-Mateos, Karol Carrillo-Sánchez, Norma Salaiza-Suazo, Georgina Carrada-Figueroa, Santiago March-Mifsut and Ingeborg Becker. “Disease severity in patients infected with Leishmania mexicana relates to IL-1β. PLoS” Neglected Tropical Diseases (2012).

Jiménez-López S, Mancera-Martínez E, Donayre-Torres A,  Rangel-Escareño C,  Uribe Figueroa L,  March-Mifsut S, Jiménez-Sánchez G and Sanchez de Jimenez “Expression Profile of Maize Zea mays L. Embryonic Axes During Germination: Translational Regulation of Ribosomal Protein mRNAs.” Plant and Cell Physiology (2011)

Maria E Frigolet, Nimbe Torres, Laura Uribe-Figueroa, Claudia Rangel, Gerardo Jimenez-Sanchez and Armando Tovar-Palacio. “White adipose tissue genome wide-expression profiling and adipocyte metabolic functions after soy protein consumption in rat.” The Journal of Nutritional Biochemistry (2010)

Co-presented with Irma Aguilar-Delfin and David L. Wild. “Inference of Key Transcriptional Regulators in Endothelial Cell Apoptosis using Bayesian State Space Models.” Conference Presentation. Proceedings of the 8th International Conference for the Critical Assessment of Microarray Data Analysis CAMDA, 2008.

Co-authored with D. Mendoza-Villanueva, J Diaz-Chavez, L Uribe-Figueroa, A Hidalgo-Miranda, S March-Mifsut, G Jimenez-Sanchez, P F Lambert and P Gariglio. “Gene Expression Profile of Cervical and Skin Tissues from Human Papillomavirus Type 16 E6 Transgenic Mice.” BMC Cancer 8 (2008):347. oi:10.1186/1471-2407-8-347

Co-authored with M. Louise Hull, Jane M. Godsland, John R. Doig, Claire M. Johnson, Stephen C. Phillips, Stephen K. Smith, Simon Tavaré, Cristin G. Print, and D. Stephen Charnock-Jones. “Endometrial-Peritoneal Interactions during Endometriotic Lesion Establishment.” Am J Pathol August 7 (2008). doi:10.2353/ajpath.2008.071128

Computational Methods for Molecular Biology
Introduction to Scientific Computing
Grants: Carlos Slim Health Institute